dogs and rabbits,12,15,16 clinical studies evaluating their use in dogs with tracheal collapse have not been reported pre-viously. Happy Pets Pulmoquin 60mL Ambroxol Hydrochloride (Mucolytic) 30mg/5 mL Syrup Indications: Aids in the treatment of catarrhal inflammation of the bronchi and the upper respiratory tract in horses and dogs. It is common for fungal infections to require several weeks of treatment. For example, small dogs often receive a total dose of 15 mg and large dogs a total dose of 30 mg. Another way that Fexofenadine is dosed in dogs is by the total dose. Several repeated-dose studies were carried out in the dog using oral and parenteral routes of administration. 16 mg/kg in guinea pigs it increased dose-dependently bronchialsecretion (PuschmannandEngelhorn1978).In¨ rats ambroxol suppressed citric-acid induced cough with Core Safety Profile Active substance: Ambroxol Pharmaceutical form(s)/strength: Syrup, 6mg/ml Film-coated tablets, 60mg Powder for oral solution (sachet) 60mg Dose based on codeine (1-2 mg/kg q8-12 hrs) but limited by acetaminophen (not to exceed 10-15 mg/kg q8-12hrs) Example: 1-2 tablets listed at left per 30 kg dog q8-12hrs Canine Quick Dosage Sheet The International Veterinary Academy of Pain Management (IVAPM) is the leading forum and educational source for veterinary professionals interested Dogs, and particularly cats, are extremely sensitive to acetaminophen and will develop sever methemoglobinemia and liver damage within hours of ingestion. Preliminary pharmacokinetic studies have established the safety of the drug, and the recommended dose is 0.01 mg/kg parenterally or 0.625 mg/cat PO BID. One study suggested higher dosages once daily has been effective in some dogs (9 mg per pound). Studies on the effects of dembrexine on ... ambroxol showed no effect on fertility and reproduction in rats at doses up to 640 mg/kg bw, no Because of the pill sizes, dosages are often rounded to the closest tablet size. Ambroxol Weiser Figure 1 Structuresof(A)vasicine,(B)bromhexine,and(C)ambroxol. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. 5. From the repeated dose studies in dogs a NOEL of 2 mg per kg bodyweight per day was established. In dogs, the usual dose is 2.5 mg to 5 mg per pound (5 to 10 mg/kg) one to two times per day orally. Dembrexine was not teratogenic in rabbits or rats. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. The dose for cats is 2.5 to 5 mg per pound (5 to 10 mg/kg) every 12 to 24 hours. The recommended dose of sustained-release theophylline in cats is 20 to 25 mg/kg PO Q 24 H in the evening (ie, one 100-mg tablet/cat/day). Only a few reports describe the implantation of intraluminal endoprostheses in dogs.9,18–21 Based on initial experience in 7 dogs with severe tracheal collapse, the implantation of self-expanding stainless-steel Theophylline is typically used more often in dogs than cats, given variable efficacy and, perhaps, less need for chronic bronchodilator therapy in cats. Itraconazole should be given with food. Dosage and Administrations Horses: 60mL 3x a day for 5 - 7 days Dogs: 5-10mL 2x a day for 5 - 7 days Ambroxol for treatment in small dogs Download Here Free HealthCareMagic App to Ask a Doctor All the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice. In a 3-month study using oral doses of 0, 0.4, 4 and 20 mg/kg bw per day, a dose-related tachycardia was apparent after the first dose and no NOEL was established. 9. Cardiotoxicity was the most notable finding in these studies. Small dogs can receive 0.625–1.25 mg PO every 12 hours, medium-sized dogs are given 1.25–2.5 mg PO every 12 hours, and larger dogs receive 2.5–5 mg PO every 12 hours. Closest tablet size dogs ( 9 mg per pound ) established the safety the! Were carried out in the dog using oral and parenteral routes of administration 5 per. 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